3xTgAD mice exhibit altered behavior and elevated Aβ after chronic mild social stress
SM Rothman, N Herdener, S Camandola, SJ Texel… - Neurobiology of …, 2012 - Elsevier
… 3xTgAD mice display vulnerability to chronic stress and whether chronic stress exacerbates
AD pathology and behavioral … 6-hour stress period 3xTgAD mice experienced a sustained …
AD pathology and behavioral … 6-hour stress period 3xTgAD mice experienced a sustained …
3xTg-AD mice exhibit an activated central stress axis during early-stage pathology
EK Hebda-Bauer, TA Simmons, A Sugg… - Journal of …, 2013 - content.iospress.com
… when 3xTg-AD mice show mild behavioral changes, suggesting … observed mild altered
emotionality in six-month-old 3xTg-AD mice… social stress as evidenced by elevated CORT levels …
emotionality in six-month-old 3xTg-AD mice… social stress as evidenced by elevated CORT levels …
Endocrine stress responsivity and social memory in 3xTg-AD female and male mice: A tale of two experiments
ET Nguyen, D Selmanovic, M Maltry, R Morano… - … and Behavior, 2020 - Elsevier
… heightened stress-induced corticosterone levels and Aβ … Although 3xTg-AD mice do not
display elevated basal … 3xTg mice (ie, 4 months) already exhibit altered mRNA expression of …
display elevated basal … 3xTg mice (ie, 4 months) already exhibit altered mRNA expression of …
Age-related changes in social behaviours in the 5xFAD mouse model of Alzheimer's disease
F Kosel, PT Munoz, JR Yang, AA Wong… - Behavioural Brain …, 2019 - Elsevier
… Evidence for increased sociability in the 3xTg-AD mouse … accelerated Aβ pathology, transgenic
5xFAD mice exhibit deficits … exhibit abnormal responses to social odour cues and altered …
5xFAD mice exhibit deficits … exhibit abnormal responses to social odour cues and altered …
Chronic mild sleep restriction accentuates contextual memory impairments, and accumulations of cortical Aβ and pTau in a mouse model of Alzheimer's disease
SM Rothman, N Herdener, KA Frankola, MR Mughal… - Brain research, 2013 - Elsevier
… of Aβ oligomers and pTau were not significantly changed in … to cause a sustained level of
stress in 3xTgAD mice. In studies … to acclimate to social stress, 3xTgAD mice also display an …
stress in 3xTgAD mice. In studies … to acclimate to social stress, 3xTgAD mice also display an …
A ketone ester diet exhibits anxiolytic and cognition-sparing properties, and lessens amyloid and tau pathologies in a mouse model of Alzheimer's disease
Y Kashiwaya, C Bergman, JH Lee, R Wan, MT King… - Neurobiology of …, 2013 - Elsevier
… the behavioral effects of the ketone ester on 3xTgAD mice, … line of 3xTgAD mice used in
the present study, Aβ and pTau … of age and progressively increase thereafter, with anxiety …
the present study, Aβ and pTau … of age and progressively increase thereafter, with anxiety …
Alcohol drinking exacerbates neural and behavioral pathology in the 3xTg-AD mouse model of Alzheimer's disease
JL Hoffman, S Faccidomo, M Kim, SM Taylor… - International review of …, 2019 - Elsevier
… markers of AD pathology in 3xTg-AD mice: Aβ 42/40 ratio in the … of alcohol intake altered
spatial learning by 3xTg-AD mice or … of 3xTg-AD mice as a translational approach to increase …
spatial learning by 3xTg-AD mice or … of 3xTg-AD mice as a translational approach to increase …
Prolonged running, not fluoxetine treatment, increases neurogenesis, but does not alter neuropathology, in the 3xTg mouse model of Alzheimer's disease
MW Marlatt, MC Potter, TA Bayer, H van Praag… - … and Neural Plasticity, 2013 - Springer
… in middle-age in the 3xTg AD mice. Such a design bears relevance … We here show that
despite the loss of the behavioral … also showed that amitriptyline increased Aβ deposition in the …
despite the loss of the behavioral … also showed that amitriptyline increased Aβ deposition in the …
Actions of brain-derived neurotrophic factor and glucocorticoid stress in neurogenesis
T Numakawa, H Odaka, N Adachi - International journal of molecular …, 2017 - mdpi.com
… altered neurogenesis, and show an interesting effect of GCs: … -transgenic mouse model of
AD (3xTgAD mice expressing … chronic mild social stress, whereas such an elevated Aβ and …
AD (3xTgAD mice expressing … chronic mild social stress, whereas such an elevated Aβ and …
[HTML][HTML] Translational modeling of psychomotor function in normal and AD-pathological aging with special concerns on the effects of social isolation
L Castillo-Mariqueo, L Giménez-Llort - Frontiers in Aging, 2021 - frontiersin.org
… the 3xTg-AD/ISO mice subgroup (n = 7) had a high motor … In particular, the grip has been
described as an alteration of … of places, 3xTg-AD mice exhibit these behaviors, which delays the …
described as an alteration of … of places, 3xTg-AD mice exhibit these behaviors, which delays the …